Sussex Police seized the plants at the former Brickmakers Arms on New Road, Ridgewood.
Officers from East Sussex’s Tactical Enforcement Unit (TEU) gained entry to the former pub on Tuesday 25 April following reports of suspicious activity from members of the public.
They seized cannabis plants alongside growing equipment.
The seized cannabis plants were in the early stages of growth
Superintendent Till Sanderson said: “The site was previously found to be a cannabis factory in May 2021, which was disrupted, but members of the public thought it had started up again.
“It looks like we disrupted the grow at an early stage. The offenders had spent a considerable amount of time, effort and money in constructing the site which they have now thankfully lost.
“Cannabis is a harmful, banned substance and its cultivation, sale and distribution brings criminality to an area. It can lead to more serious crimes and goes hand-in-hand with violence, exploitation and addiction, sowing devastation among our communities.
“This operation proves that we will continue to be relentless in our pursuit of perpetrators, while working with our partners to address the root causes of this behaviour and safeguard those most at risk of harm.”
Flooding forces Eastbourne roller-skating rink to close
£50,000 fundraising goal set for 'significant' Arlington Stadium repairs
Hailsham main road to remain closed for further five weeks as works move to second phase
Eastbourne MP to meet with new South East Water CEO to discuss 'ongoing challenges'
South East Water looking to repair leak in Eastbourne road ‘as soon as possible’
East Hoathly Care Home Named in Care Experts UK Top 10
Eastbourne man, 23, jailed for running Brighton drugs line
Fourth member of family pulled from the water in Shoreham sadly dies