The A27 links key coastal communities between Eastbourne and Portsmouth and improvement work will continue this autumn and winter.
Work has been taking place already on Old Shoreham Road, Southwick tunnel and the Patcham viaduct.
Planned work is due to start shortly between Falmer and Southerham roundabout. Works will also start at the Adur viaduct and at Salvington in November.
Improvements include road resurfacing, renewal of road markings, bridge joint replacements, and updated signage.
Full details on the work are available from National Highways
Ashdown Radio teams up with East Sussex College for a charity fundraiser
Former Eastbourne Punch and Judy man to sign copies of book in Hailsham
Three arrested following police pursuit in East Sussex
Man jailed after Asda van theft and pursuit in Eastbourne
Freedom Leisure launches Swimathon 2026 at Crowborough Leisure Centre with Duncan Goodhew MBE
Councillors to consider more than 200 homes in Uckfield area
ABBA tribute Björn Again confirm Eastbourne date
Bluebell Walk has raised over £1million for local charities